Calendula clinical trials

This systematic review evaluates the role of Calendula officinalis flower extract as monotherapy compared to control for wound healing in vivo. Findings from the review on acute wound healing showed faster resolution of the inflammation phase with increased production of granulation tissue in the test groups treated with extract. These findings were consistent in five animal studies and one randomized clinical trial. Chronic wound healing studies were varied. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U.

Federal Government. Read our disclaimer for details. Last Update Posted : September 17, Study Description. MedlinePlus related topics: Breast Cancer. Drug Information available for: Calendula officinalis. FDA Resources.

Arms and Interventions. Essex cream is applied twice daily on the skin in the radiated area during the entire treatment period and until the skin reaction subsided.

Outcome Measures. Secondary Outcome Measures : Quality of life in relation to skin reaction [ Time Frame: 8 weeks ] Measurements of sleep disturbances acc. Other Outcome Measures: Impact of smoking habits on the intensity of the skin reaction [ Time Frame: 8 weeks ] Collection of data on smoking habits and measurements of carbon monoxide in exhaled air.

Klouchek-Popova, E. Influence of the physiological regeneration and epithelialization using fractions isolated from Calendula officinalis. Acta Physiol Pharmacol Bulg. Kumar, S. Management of skin toxicity during radiation therapy: a review of the evidence.

Imaging Radiat. Kundakovic, T. Treatment of venous ulcers with the herbal-based ointment Herbadermal R : a prospective non-randomized pilot study. Controlled study of three ointments for the local management of 2nd and 3rd degree burns. Clin Trials Meta-analysis ; Machado, M.

Management of two cases of desquamative gingivitis with clobetasol and Calendula officinalis gel. Univ Palacky. McQuestion, M. Evidence-based skin care management in radiation therapy. Oncol Nurs ;22 3 Naseer, S. Role of Calendula extract in treatment of anal fissures. Neto, J. Treatment of varicose ulcer and skin lesions with calendula.

Revista de Ciencias Farm Sao Paulo ; Pommier, P. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.

Gillett J. Complementary and alternative medicine use in radiotherapy: What are patients using? Chrystal K. Paterson D. Randomized intra-patient controlled trial of Mepilex Lite dressings versus aqueous cream in managing radiation-induced skin reactions postmastectomy. Cancer Sci. Diggelmann K. Mepilex Lite dressings for the management of radiation-induced erythema: A systematic inpatient controlled clinical trial.

Herst P. Prophylactic use of Mepitel Film prevents radiation-induced moist desquamation in an intra-patient randomised controlled clinical trial of 78 breast cancer patients. Protecting the radiation-damaged skin from friction: A mini review. Graham P. Mannix C. A feasibility study of low-cost, self-administered skin care interventions in patients with head and neck cancer receiving chemoradiation. Hoopfer D. Breast Cancer. Wells M. Does aqueous or sucralfate cream affect the severity of erythematous radiation skin reactions?

A randomised controlled trial. Salvo N. Prophylaxis and management of acute radiation-induced skin reactions: A systematic review of the literature. Campbell I. Can patients wash during radiotherapy to the breast or chest wall? A randomized controlled trial. Roy I. The impact of skin washing with water and soap during breast irradiation: A randomized study. Westbury C. Advice on hair and scalp care during cranial radiotherapy: A prospective randomized trial.

Olsen D. Williams M. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Heggie S. A Phase III study on the efficacy of topical aloe vera gel on irradiated breast tissue.

Cancer Nurs. Maiche A. Skin protection by sucralfate cream during electron beam therapy. Acta Oncol. Elliott E. Phase III Trial of an emulsion containing trolamine for the prevention of radiation dermatitis in patients with advanced squamous cell carcinoma of the head and neck: Results of Radiation Therapy Oncology Group Trial Bostrom A.

Potent corticosteroid cream mometasone furoate significantly reduces acute radiation dermatitis: Results from a double-blind, randomized study. Schmuth M. Topical corticosteroid therapy for acute radiation dermatitis: A prospective, randomized, double-blind study. Potera M. Prophylaxis of radiation dermatitis with a topical cortisone cream. Kumar S. Management of skin toxicity during radiation therapy: A review of the evidence.

Imaging Radiat. Wong R. Care Cancer. Pommier P. Phase III randomized trial of Calendula officinalis compared with trolamine for the prevention of acute dermatitis during irradiation for breast cancer.

Hunt C. Histone modifications and DNA double-strand break repair after exposure to ionizing radiations. Janko M. IL-1 generated subsequent to radiation-induced tissue injury contributes to the pathogenesis of radiodermatitis. Simonen P. Do inflammatory processes contribute to radiation induced erythema observed in the skin of humans?

Heissig B. Low-dose irradiation promotes tissue revascularization through VEGF release from mast cells and MMPmediated progenitor cell mobilization. Behrends U. Ionizing radiation induces human intercellular adhesion molecule-1 in vitro. Canney P.